Doxycycline Hyclate Cost


Written by:  Howmuchisit.org Staff
Last Updated:  August 13, 2018

Doxycycline hyclate, the generic version of Acticlate and Vibramycin, is a prescription-based drug designed to treat many infections, including dental, respiratory, skin and urinary tract infections, to name a few.  Aside from treating infections, the medication can also treat malaria, some sexually transmitted disease, Lyme disease and acne.

How much does doxycycline hyclate cost?

The cost of doxycycline, as with any prescription, will depend on the dosage, your health insurance policy and the pharmacy you choose.  From our research, without any health insurance, you should be prepared to spend about $0.95 per capsule, but this price can drop if you were to be prescribed a larger prescription at once.

As the dosages and quantities can affect the price, we organized the price estimates we received from popular pharmacy chains such as Sam’s Club, Walmart, Costco, CVS and Walgreens.

DosagePrice Estimate (without insurance)
20MG- 30 capsules: $20
- 50 capsules: $25
- 100 capsules: $37
50MG- 50 capsules: $50
- 100 capsules: $75
- 150 capsules: $100
100MG- 50 capsules: $50
- 100 capsules: $65
- 150 capsules: $82

Being a generic prescription, almost all private health insurance policies and Medicare policies will cover the drug, with co-pays reported to be anywhere from $1 to more than $80.  Check with both your private health insurance policy and your pharmacy to see what you will be responsible for as all health insurance policies will greatly vary.

Doxycycline overview

This medication, also referred to as a tetracycline antibiotic, is designed to treat a variety of bacterial infections, including those that often cause acne.  It can also be used to prevent malaria.  This medication can only treat bacterial infections and will not work on viral infections such as the common cold and/or flu.

To use, it will often be taken orally at least one to two hours before a meal, usually once or twice a day, as directed by your doctor.  If taken for malaria, for example, then it’s taken once a day, usually one to two days before your travel date and throughout your trip, even when you return home, up to four weeks.  It’s best to take the medication with a full glass of water unless your doctor tells you otherwise.  If stomach upset occurs while taking the medication, then you may want to consider taking it with food or milk as this is known to help; however, do keep in mind that it may not work as well as anything high in calcium can cause the medication to lose its effectiveness.

The liquid form of this medication must be shaken well before and the special spoon inside should be used for appropriate measurements.

Always take the medication as prescribed by your doctor, even if you feel the symptoms are disappearing.  If you were to stop the medication too early, for instance, then it could allow the bacteria to continue to grow again.

Doxycycline side effects

Commonly reported side effects include an upset stomach, diarrhea, vomiting and nausea.  If any side effects persist or even worsen, always talk with a medical professional immediately for more information on the next steps to take.

Serious side effects, albeit rare, can still occur, including kidney problems, painful swallowing skull pressure, severe headaches, vision changes and/or persistent vomiting.  In some cases, again, being rare, serious allergic reactions can occur.

This is not a full list of side effects; to see the full list, refer to this official FDA documentation.

Tips to know

As with any prescription, always tell your doctor your medical history, especially if you have a history of problems swallowing and/or esophagus-related problems such as heartburn.

As the medication does have live bacterial, vaccinations may not work as they should if you were to get vaccinated while on the medicine.

In some cases, this medication may make you sensitive to the sun.  Limit your sun exposure and as always, avoid tanning beds and use the appropriate amount of sunscreen when out.

Store at room temperature, away from younger children, pets and moisture.  Refer to the packaging directions as to how to properly store your medications.


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