How Much Does a Euflexxa Injection Cost?


Written by:  Howmuchisit.org Staff
Last Updated:  August 10, 2018

Euflexxa is an injection which is used to help alleviate knee pain due to osteoarthritis.  These injections will often be considered as a last resort when pain medication or physical therapy has proven to be ineffective.  This injection is only designed for the knee and must be performed by a doctor or qualified health professional.

The reported Euflexxa costs per injection

The costs of a Euflexxa injection will greatly depend on your doctor administering it and your health insurance policy.  From our research, the cost of the injection, without any insurance, will often be in the $350 to $1,000 range, but for those with insurance, the costs may be much less.   To see if these injections will be covered by your health insurance policy, the manufacturer of the drug created a search portal to offer you a definite answer.

MDSave.com, a digital portal which connects you with physicians offering the injection, had listings in the $348 range.

On this Topix.com forum thread, someone did note they received the injections and paid about $350 after insurance paid its portion.

The extra costs to consider

Keep in mind this is the price range for the injections only and will not include the costs of the doctor’s visit and any follow-up visits recommended by your doctor.

Also, if the injections do work for your situation, then you should be prepared to come back every six to 12 months for another series of injections.

What is Euflexxa?

Hyaluronate, a substance similar to what naturally occurs in the human joints, help these joints work properly by acting as a lubricant and shock absorber.

With osteoarthritis, the cartilage surface of the joint will begin to wear away and joint fluid will slowly dissipate.  Injecting this special protein can help relieve the pain and stiffness as it will help lubricate and shock-absorb the affected worn-out surface.

How is it injected

Performed either in a hospital or doctor’s setting, an injection is made directly into the knee joint.  These injections, over the course of three weeks, will need to be administered once a week for a total of three shots.  Stephanie E. Siegrist, M.D. at KnowYourBones.com recommends this injection for patients who either had an allergic reaction to Synvisc, a similar injection in the past or patients who have Aetna insurance.

After the injection, your physician will ask you to limit your activity for the next 48 hours, resting your knee with a compress to prevent your knee from swelling.

Euflexxa side effects (source)

Facts to know

These injections will not work for everyone.  In fact, even after six to 12 months, some people will only feel less soreness and/or stiffness for the next six to 12 months after the injections.  Your results will vary.  The injections, even if they work, will last up to 12 months.

Euflexxa is just one of the many “brands” of this kind of treatment.  Other brands include Synvisc and GelOne.

These injections, again, will not cure your pain as your doctor will still recommend managing your weight, performing low-impact exercises and treating your knee with respect.

Euflexxa reviews from around the Internet

Over 145 users on Drugs.com gave the injections a 6.7 out of 10.  The positive reviewers noted much less pain, even six to eight months after the injections, whereas the negative reviewers, for the most part, stated they felt no relief at all.

300 members on WebMD.com gave the injections a 3.03 out of a five-star review.  Like the Drugs.com reviewers, it was either real positive, working quite well, or extremely negative, with no notice of improvement seen.


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