How Much Does Ampyra Cost?

Written by: Staff

Ampyra, a potassium channel blocker prescription drug, is designed to help patients suffering from multiple sclerosis and a slower rate of walking speed, one of the most reported challenges of having MS.

Marketed as the only drug designed to increase an MS patient’s walking speed, each tablet contains 10 milligrams of dalfampridine, designed to help conduct nerve signals by improving the ability of the nerve fibers that were damaged by demyelination due to MS.

How much does Ampyra cost?

The costs of Ampyra, as with most medications, will depend on the pharmacy you use, your health insurance policy and the quantity prescribed.  As there is no generic version at the time of this publishing, your only choice will be the branded tablets.  Since there are a few quantities available, we included the average prices we found when we called local pharmacies such as CVS, Walgreens, Costco, Sam’s Club and Walmart.

QuantityAverage Price Reported (without insurance)
30 tablets (10mg)$1,150
60 tablets (10mg)$2,500
180 tablets (10mg)$7,300

As for health insurance policies, it appears most policies, including Medicare, will cover it, but the coverages will greatly vary as policies differ with co-pays and deductibles.  Even if covered, you could still find yourself paying hundreds or even thousands, especially if you didn’t meet your deductibles for the year.

According to the Multiple Sclerosis News Today, the out-of-pocket costs can be around $500, a reason why the author stopped using it.

How to save on Ampyra

Manufacturer coupon:  The official manufacturer of the drug does offer a free 60-day trial for patients, but in order to take advantage of the offer, there are eligibility requirements you must meet.  For one, your healthcare provider must determine you are a candidate for the prescription.  If qualified, patients on any government-funded program, such as Medicare or Medicare, are not eligible, nor are patients who had a prescription in the past 12 months.  This information is only accurate at the time of this publishing and is subject to change.  For those who are interested, you can follow this link and look for the downloadable PDF you can take to your doctor for more information.

Patient support services:  Aside from the coupon option, the manufacturer also offers a patient support services link that can help cover out-of-pocket costs of the medication.  To learn more about the program and see if you qualify, you can follow this link or call 1-888-881-1918.

Patient assistance programs:  Even if you have health insurance, you may find a hard time affording the prescription.  For this reason, there are assistance programs out there that are designed to help those on limited incomes or those with limited or no health insurance at all.  The PAN Foundation Patient Assistance, for example, can help you pay as little as $0 out of pocket if you qualify.  To see if you qualify, like the manufacturer coupon above, you can follow the link for more information to enroll.

Coupons via third parties:  Popular prescription coupon websites, such as, can help you save money, even if you do not have a health insurance policy or even adequate policy.  Working a lot like health insurance, you simply search the drug you need, the pharmacy you want to use, and then, if a coupon is available, you can print it and take it to your local pharmacy, showing it just as you would a health insurance card.

Ampyra side effects

Via multiple clinical trials, the most commonly reported side effects include urinary tract infections, insomnia, dizziness, headaches asthenia, back pain, multiple sclerosis relapses, flu-like symptoms, constipation, indigestion and/or throat pain.  These were the most commonly noted side effects and not considered to be a full list; to see all of the side effects, refer to this FDA guide.  As with any side effects noted by any prescription drug, always talk with your doctor immediately for any concerns you may have.

Tips to know

Ampyra, available as an extended-release tablet, is often recommended twice a day, about 12 hours apart, but as with any prescription drug, closely follow your doctor’s orders.  Never take more, less or stop without your doctor’s permission.  It can be taken with or without food, but should always be swallowed whole.

The drug is said to work by blocking the tiny pores on the surface of nerve fibers, known as potassium channels, as doing so may help improve the ability of these nerve fibers that were damaged by demyelination due to MS.

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