How Much Does Duexis Cost?


Written by:  Howmuchisit.org Staff
Last Updated:  August 13, 2018

Duexis, a combination of famotidine, a type of antihistamine which blocks the release of the stomach acid and helps prevent stomach problems from the ibuprofen, and ibuprofen, a non-steroidal anti-inflammatory drug, is a prescription medication in the form of a tablet used to treat the symptoms associated with arthritis pain.

How much does Duexis cost?

The cost of Duexis will depend on a few factors, just like any other medication, including your health insurance policy, the dosage, quantity and where you have your prescription filled.  Based on all of these factors and our research, the total cost of Duexis can vary anywhere from $850 for 30 800mg tablets to as much as $2,500+ for 90 800mg tablets.  As of this publishing, Duexis is only available in 26.6 mg-800 mg strength.

30 tablets$850
60 tablets$1,700
90 tablets$2,500

As for health insurance coverage, GoodRX.com does note that Medicare does not cover this drug, but your co-pay with other insurance companies will depend, with co-pay price ranges reportedly to be in the $95 to $2,855 range.  To be for certain, however, check with your health insurance provider or talk with your local pharmacy to see what you may be responsible for.  Using your health insurance isn’t the only way to save as there are other ways, which we get into below, as to ways to save on Duexis.

Why is Duexis so expensive?

The medication was approved in 2011, and as noted, it’s simply a combination of both ibuprofen (Advil) and famotidine (Pepcid) at a dose of 800 mg and 26.6 mg.  While you can buy ibuprofen and famotidine over the counter, the combination of these drugs are designed to help protect the stomach from the ibuprofen, but according to this GoodRX.com guide, there’s no evidence that a combination pill works better than taking the prescriptions separately.

As for the expensive price tag, the answer isn’t definitive, but from answers from representatives in the past, they claim the price is based on the value it brings to patients, while some economists simply call the price tag a “scam.”

How to save money on Duexis

Manufacturer coupon program:  The official manufacturer of the drug, Horizon Pharma offers the Duexis Savings Plus Program, a savings program designed to help reduce your out-of-pocket costs to as little as $0, with a maximum savings of $1,200.  According to the terms and conditions on the website, you will need to be an eligible patient with commercial insurance and the offer cannot be combined with any other offers, including those who are on government assistance.  To learn more about the program, refer to the official Duexis website to apply.

A separate prescription?  As noted, Duexis is a combination of two medications, which can be prescribed separately, and in most cases, the separate prescription can be much cheaper in some cases; however, as the label does note, it clearly states “do not substitute DUEXIS with the single-ingredient products of ibuprofen and famotidine.”  Talk with your doctor about separate prescriptions if you’re concerned about the price at your local pharmacy.  The New York Times, for example, noted that if the two drugs were prescribed separately, it would cost no more than $40 a month.

Support programs:  Aside from the coupon program and your health insurance, countless non-profit organizations exist that are designed to help pay for your medication as long as you meet the eligibility requirements.  The Horizon Patient Assistance Program, for example, can help you out financially as long as you meet the restrictions such as a proof of household income and a valid prescription.  Other support programs do exist and a simple Google search can often yield multiple results.

Longer supply:  If your doctor knows you will need the medication for more than 30 days, then you may want to ask for a longer supply since this can sometimes cut down the costs of the medication by 5% or more.

Duexis side effects

This is not a full list of side effects; for an in-depth list, refer to this FDA guide

Tips to know

As of 2018, no generic equivalent is available.

For rheumatoid arthritis and osteoarthritis sufferers, your doctor will more than likely prescribe three tablets per day.


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